CATH Classification

Domain Context

CATH Clusters

Superfamily Fibronectin, type II, collagen-binding
Functional Family 72 kDa type IV collagenase

Enzyme Information

3.4.24.24
Gelatinase A.
based on mapping to UniProt P08253
Cleavage of gelatin type I and collagen types IV, V, VII, X. Cleaves the collagen-like sequence Pro-Gln-Gly-|-Ile-Ala-Gly-Gln.
-!- Belongs to peptidase family M10B.

UniProtKB Entries (1)

P08253
MMP2_HUMAN
Homo sapiens
72 kDa type IV collagenase

PDB Structure

PDB 1EAK
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of Human Mmp-2 Reveals a New P
Bergmann, U., Tuuttila, A., Morgunova, E., Tryggvason, K.
To be Published