CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.1120 | Arylsulfatase, C-terminal domain |
|
3.30.1120.150 |
Domain Context
CATH Clusters
| Superfamily | 3.30.1120.150 |
| Functional Family |
Enzyme Information
| 2.3.1.118 |
N-hydroxyarylamine O-acetyltransferase.
based on mapping to UniProt Q00267
Acetyl-CoA + an N-hydroxyarylamine = CoA + an N-acetoxyarylamine.
-!- The enzyme from liver, but not that from bacteria, can also catalyze N-acetylation of arylamines and N,O-acetylation of arylhydroxamates.
|
| 2.3.1.5 |
Arylamine N-acetyltransferase.
based on mapping to UniProt Q00267
Acetyl-CoA + an arylamine = CoA + an N-acetylarylamine.
-!- Wide specificity for aromatic amines, including serotonin; also catalyzes acetyl-transfer between arylamines without CoA.
|
UniProtKB Entries (1)
| Q00267 |
NHOA_SALTY
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Arylamine N-acetyltransferase / N-hydroxyarylamine O-acetyltransferase
|
PDB Structure
| PDB | 1E2T |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure of Arylamine N-Acetyltransferase Reveals a Catalytic Triad
Nat.Struct.Biol.
|