CATH Classification

Domain Context

CATH Clusters

Superfamily Glycoside hydrolase, family 7, domain
Functional Family

Enzyme Information

3.2.1.4
Cellulase.
based on mapping to UniProt P56680
Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.
-!- Will also hydrolyze 1,4-linkages in beta-D-glucans also containing 1,3-linkages.

UniProtKB Entries (1)

P56680
GUN1_HUMIN
Humicola insolens
Endoglucanase 1

PDB Structure

PDB 1DYM
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of the family 7 endoglucanase I (Cel7B) from Humicola insolens at 2.2 A resolution and identification of the catalytic nucleophile by trapping of the covalent glycosyl-enzyme intermediate.
MacKenzie, L.F., Sulzenbacher, G., Divne, C., Jones, T.A., Woldike, H.F., Schulein, M., Withers, S.G., Davies, G.J.
Biochem.J.