CATH Classification

CATH Clusters

Superfamily Glutaredoxin
Functional Family Glutathione S-transferase Mu 2

Enzyme Information

2.5.1.18
Glutathione transferase.
based on mapping to UniProt P08515
RX + glutathione = HX + R-S-glutathione.
-!- A group of enzymes of broad specificity. -!- R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. -!- Also catalyzes the addition of aliphatic epoxides and arene oxides to glutathione, the reduction of polyol nitrate by glutathione to polyol and nitrile, certain isomerization reactions and disulfide interchange. -!- Formerly EC 1.8.6.1, EC 2.5.1.12, EC 2.5.1.13, EC 2.5.1.14 and EC 4.4.1.7.

UniProtKB Entries (2)

P02679
FIBG_HUMAN
Homo sapiens
Fibrinogen gamma chain
P08515
GST26_SCHJA
Schistosoma japonicum
Glutathione S-transferase class-mu 26 kDa isozyme

PDB Structure

PDB 1DUG
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of the fibrinogen gamma-chain integrin binding and factor XIIIa cross-linking sites obtained through carrier protein driven crystallization.
Ware, S., Donahue, J.P., Hawiger, J., Anderson, W.F.
Protein Sci.