CATH Classification

Domain Context

CATH Clusters

Superfamily alpha/beta hydrolase
Functional Family

Enzyme Information

3.1.1.3
Triacylglycerol lipase.
based on mapping to UniProt O59952
Triacylglycerol + H(2)O = diacylglycerol + a carboxylate.
-!- The pancreatic enzyme acts only on an ester-water interface; the outer ester links are preferentially hydrolyzed.

UniProtKB Entries (1)

O59952
LIP_THELA
Thermomyces lanuginosus
Lipase

PDB Structure

PDB 1DT5
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural origins of the interfacial activation in Thermomyces (Humicola) lanuginosa lipase.
Brzozowski, A.M., Savage, H., Verma, C.S., Turkenburg, J.P., Lawson, D.M., Svendsen, A., Patkar, S.
Biochemistry