CATH Classification

Domain Context

CATH Clusters

Superfamily Alpha carbonic anhydrase
Functional Family Alpha carbonic anhydrase 3

Enzyme Information

4.2.1.1
Carbonic anhydrase.
based on mapping to UniProt P23589
H(2)CO(3) = CO(2) + H(2)O.
-!- The enzyme catalyzes the reversible hydration of gaseous CO(2) to carbonic acid, which spontaneously converts to hydrogencarbonate under neutral pH. -!- It is widespread and found in archaea, bacteria, and eukaryotes. -!- Three distinct classes exist, and appear to have evolved independently.

UniProtKB Entries (1)

P23589
CAH5A_MOUSE
Mus musculus
Carbonic anhydrase 5A, mitochondrial

PDB Structure

PDB 1DMY
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure determination of murine mitochondrial carbonic anhydrase V at 2.45-A resolution: implications for catalytic proton transfer and inhibitor design.
Boriack-Sjodin, P.A., Heck, R.W., Laipis, P.J., Silverman, D.N., Christianson, D.W.
Proc.Natl.Acad.Sci.USA