CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.740
Functional Family Dimethyl sulfoxide reductase A subunit

Enzyme Information

1.7.2.3
Trimethylamine-N-oxide reductase (cytochrome c).
based on mapping to UniProt Q52675
Trimethylamine + 2 (ferricytochrome c)-subunit + H(2)O = trimethylamine N-oxide + 2 (ferrocytochrome c)-subunit + 2 H(+).
-!- The cytochrome c involved in photosynthetic bacteria is a pentaheme protein. -!- The reductant is a membrane-bound multiheme cytochrome c. -!- Also reduces dimethyl sulfoxide to dimethyl sulfide.
1.8.5.3
Dimethylsulfoxide reductase.
based on mapping to UniProt Q52675
Dimethylsulfide + menaquinone + H(2)O = dimethylsulfoxide + menaquinol.
-!- Also reduces pyridine N-oxide and trimethylamine N-oxide, with lower activity, to the corresponding amines.

UniProtKB Entries (1)

Q52675
DSTOR_RHOCA
Rhodobacter capsulatus
Dimethyl sulfoxide/trimethylamine N-oxide reductase

PDB Structure

PDB 1DMR
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Molybdenum Active Centre of Dmso Reductase from Rhodobacter Capsulatus: Crystal Structure of the Oxidised Enzyme at 1.82-A Resolution and the Dithionite-Reduced Enzyme at 2.8-A Resolution
Mcalpine, A.S., Mcewan, A.G., Shaw, A., Bailey, S.
J.Biol.Inorg.Chem.