CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family Quinoid dihydropteridine reductase

Enzyme Information

1.5.1.34
6,7-dihydropteridine reductase.
based on mapping to UniProt P11348
A 5,6,7,8-tetrahydropteridine + NAD(P)(+) = a 6,7-dihydropteridine + NAD(P)H.
-!- The substrate is the quinonoid form of dihydropteridine. -!- Not identical with EC 1.5.1.3. -!- Formerly EC 1.6.99.7 and EC 1.6.99.10.

UniProtKB Entries (1)

P11348
DHPR_RAT
Rattus norvegicus
Dihydropteridine reductase

PDB Structure

PDB 1DIR
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of a monoclinic form of dihydropteridine reductase from rat liver.
Su, Y., Skinner, M.M., Xuong, N.H., Matthews, D.A., Whiteley, J.M., Varughese, K.I.
Acta Crystallogr.,Sect.D