CATH Classification

Domain Context

CATH Clusters

Superfamily DNA Methylase, subunit A, domain 2
Functional Family

Enzyme Information

2.1.1.37
DNA (cytosine-5-)-methyltransferase.
based on mapping to UniProt P20589
S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.
-!- See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/ -!- Formerly EC 2.1.1.73.

UniProtKB Entries (1)

P20589
MTH3_HAEAE
Haemophilus aegyptius
Modification methylase HaeIII

PDB Structure

PDB 1DCT
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The crystal structure of HaeIII methyltransferase convalently complexed to DNA: an extrahelical cytosine and rearranged base pairing.
Reinisch, K.M., Chen, L., Verdine, G.L., Lipscomb, W.N.
Cell(Cambridge,Mass.)