CATH Classification

Domain Context

CATH Clusters

Superfamily D-Amino Acid Oxidase, subunit A, domain 2
Functional Family p-hydroxybenzoate hydroxylase

Enzyme Information

1.14.13.2
4-hydroxybenzoate 3-monooxygenase.
based on mapping to UniProt P20586
4-hydroxybenzoate + NADPH + O(2) = protocatechuate + NADP(+) + H(2)O.
-!- Most enzymes from Pseudomonas are highly specific for NAD(P)H (cf. EC 1.14.13.33).

UniProtKB Entries (1)

P20586
PHHY_PSEAE
Pseudomonas aeruginosa PAO1
P-hydroxybenzoate hydroxylase

PDB Structure

PDB 1D7L
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure-function correlations of the reaction of reduced nicotinamide analogues with p-hydroxybenzoate hydroxylase substituted with a series of 8-substituted flavins.
Ortiz-Maldonado, M., Gatti, D., Ballou, D.P., Massey, V.
Biochemistry