CATH Classification

Domain Context

CATH Clusters

Superfamily Tyrosyl-Transfer RNA Synthetase
Functional Family Tryptophan--tRNA ligase

Enzyme Information

6.1.1.2
Tryptophan--tRNA ligase.
based on mapping to UniProt P00953
ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophyl- tRNA(Trp).

UniProtKB Entries (1)

P00953
SYW_GEOSE
Geobacillus stearothermophilus
Tryptophan--tRNA ligase

PDB Structure

PDB 1D2R
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
2.9 A crystal structure of ligand-free tryptophanyl-tRNA synthetase: domain movements fragment the adenine nucleotide binding site.
Ilyin, V.A., Temple, B., Hu, M., Li, G., Yin, Y., Vachette, P., Carter Jr., C.W.
Protein Sci.