CATH Classification

Domain Context

CATH Clusters

Superfamily 1.10.8.60
Functional Family vesicle-fusing ATPase isoform X1

Enzyme Information

3.6.4.6
Vesicle-fusing ATPase.
based on mapping to UniProt P18708
ATP + H(2)O = ADP + phosphate.
-!- A large family of ATP-hydrolyzing enzymes involved in the heterotypic fusion of membrane vesicles with target membranes and the homotypic fusion of various membrane compartments. -!- They belong to the AAA-type (ATPase associated with a variety of cell activities) ATPase superfamily. -!- They include peroxin, which apparently is involved in Zellweger's syndrome.

UniProtKB Entries (1)

P18708
NSF_CRIGR
Cricetulus griseus
Vesicle-fusing ATPase

PDB Structure

PDB 1D2N
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of the hexamerization domain of N-ethylmaleimide-sensitive fusion protein.
Lenzen, C.U., Steinmann, D., Whiteheart, S.W., Weis, W.I.
Cell(Cambridge,Mass.)