CATH Classification

Domain Context

CATH Clusters

Superfamily Eco RI Endonuclease, subunit A
Functional Family

Enzyme Information

3.1.21.4
Type II site-specific deoxyribonuclease.
based on mapping to UniProt P43642
Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.
-!- Large group of enzymes which recognize specific short DNA sequences and cleave either within, or at a short specific distance from, the recognition site. -!- See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/

UniProtKB Entries (1)

P43642
T2MU_MYCSP
Mycoplasma sp.
Type-2 restriction enzyme MunI

PDB Structure

PDB 1D02
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of MunI restriction endonuclease in complex with cognate DNA at 1.7 A resolution.
Deibert, M., Grazulis, S., Janulaitis, A., Siksnys, V., Huber, R.
EMBO J.