CATH Classification

Domain Context

CATH Clusters

Superfamily Fibronectin, type II, collagen-binding
Functional Family Fibronectin 1a isoform 1

Enzyme Information

3.4.24.24
Gelatinase A.
based on mapping to UniProt P08253
Cleavage of gelatin type I and collagen types IV, V, VII, X. Cleaves the collagen-like sequence Pro-Gln-Gly-|-Ile-Ala-Gly-Gln.
-!- Belongs to peptidase family M10B.

UniProtKB Entries (1)

P08253
MMP2_HUMAN
Homo sapiens
72 kDa type IV collagenase

PDB Structure

PDB 1CXW
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
The second type II module from human matrix metalloproteinase 2: structure, function and dynamics.
Briknarova, K., Grishaev, A., Banyai, L., Tordai, H., Patthy, L., Llinas, M.
Structure Fold.Des.