CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.10390 | Gingipain r; domain 1 |
Domain Context
CATH Clusters
| Superfamily | Gingipain r; domain 1 |
| Functional Family | Gingipain R2 |
Enzyme Information
| 3.4.22.37 |
Gingipain R.
based on mapping to UniProt P95493
Hydrolysis of proteins and small molecule substrates, with a preference for Arg in P1.
-!- Strongly activated by glycine and stabilized by calcium. -!- Belongs to peptidase family C25.
|
UniProtKB Entries (1)
| P95493 |
CPG2_PORGI
Porphyromonas gingivalis W83
Gingipain R2
|
PDB Structure
| PDB | 1CVR |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of gingipain R: an Arg-specific bacterial cysteine proteinase with a caspase-like fold.
EMBO J.
|