CATH Classification

CATH Clusters

Superfamily 3.40.47.10
Functional Family Stilbene synthase 2

Enzyme Information

2.3.1.74
Naringenin-chalcone synthase.
based on mapping to UniProt P30074
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO(2).
-!- In the presence of NADH and a reductase, 6'-deoxychalcone is produced.

UniProtKB Entries (1)

P30074
CHS2_MEDSA
Medicago sativa
Chalcone synthase 2

PDB Structure

PDB 1CGK
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of chalcone synthase and the molecular basis of plant polyketide biosynthesis.
Ferrer, J.L., Jez, J.M., Bowman, M.E., Dixon, R.A., Noel, J.P.
Nat.Struct.Biol.