CATH Classification

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family Chymotrypsinogen A

Enzyme Information

3.4.21.1
Chymotrypsin.
based on mapping to UniProt P00766
Preferential cleavage: Tyr-|-Xaa, Trp-|-Xaa, Phe-|-Xaa, Leu-|-Xaa.
-!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.5 and EC 3.4.4.6.

UniProtKB Entries (1)

P00766
CTRA_BOVIN
Bos taurus
Chymotrypsinogen A

PDB Structure

PDB 1CBW
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structures of bovine chymotrypsin and trypsin complexed to the inhibitor domain of Alzheimer's amyloid beta-protein precursor (APPI) and basic pancreatic trypsin inhibitor (BPTI): engineering of inhibitors with altered specificities.
Scheidig, A.J., Hynes, T.R., Pelletier, L.A., Wells, J.A., Kossiakoff, A.A.
Protein Sci.