CATH Classification

Domain Context

CATH Clusters

Superfamily P1 Nuclease
Functional Family

Enzyme Information

3.1.4.3
Phospholipase C.
based on mapping to UniProt P0C216
A phosphatidylcholine + H(2)O = 1,2-diacyl-sn-glycerol + phosphocholine.
-!- The bacterial enzyme also acts on sphingomyelin and phosphatidylinositol. -!- The enzyme from seminal plasma does not act on phosphatidylinositol.

UniProtKB Entries (1)

P0C216
PHLC1_CLOPE
Clostridium perfringens str. 13
Phospholipase C

PDB Structure

PDB 1CA1
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of the key toxin in gas gangrene.
Naylor, C.E., Eaton, J.T., Howells, A., Justin, N., Moss, D.S., Titball, R.W., Basak, A.K.
Nat.Struct.Biol.