CATH Classification

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family Protease serine 2 preproprotein

Enzyme Information

3.4.21.4
Trypsin.
based on mapping to UniProt P00761
Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.
-!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.4.

UniProtKB Entries (2)

P00761
TRYP_PIG
Sus scrofa
Trypsin
P82107
BDEL_HIRME
Hirudo medicinalis
Bdellastasin

PDB Structure

PDB 1C9P
External Links
Method X-RAY DIFFRACTION
Organism Saccharomyces
Primary Citation
Structure of the complex of the antistasin-type inhibitor bdellastasin with trypsin and modelling of the bdellastasin-microplasmin system.
Rester, U., Bode, W., Moser, M., Parry, M.A., Huber, R., Auerswald, E.
J.Mol.Biol.