CATH Classification

Domain Context

CATH Clusters

Superfamily HybD-like
Functional Family

Enzyme Information

3.4.24.78
GPR endopeptidase.
based on mapping to UniProt P22321
Endopeptidase action with P4 Glu or Asp, P1 preferably Glu > Asp, P1' hydrophobic and P2' Ala.
-!- Initiates the degradation of small, acid-soluble proteins during spore germination in Bacillus megaterium. -!- Belongs to peptidase family M63.

UniProtKB Entries (1)

P22321
GPR_BACMQ
Bacillus megaterium QM B1551
Germination protease

PDB Structure

PDB 1C8B
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of a novel germination protease from spores of Bacillus megaterium: structural arrangement and zymogen activation.
Ponnuraj, K., Rowland, S., Nessi, C., Setlow, P., Jedrzejas, M.J.
J.Mol.Biol.