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CATH Classification

Domain Context

CATH Clusters

Superfamily Lumazine/riboflavin synthase
Functional Family 6,7-dimethyl-8-ribityllumazine synthase

Enzyme Information

2.5.1.78
6,7-dimethyl-8-ribityllumazine synthase.
based on mapping to UniProt Q9XH32
1-deoxy-L-glycero-tetrulose 4-phosphate + 5-amino-6- (D-ribitylamino)uracil = 6,7-dimethyl-8-(D-ribityl)lumazine + 2 H(2)O + phosphate.
-!- Involved in riboflavin biosynthesis.

UniProtKB Entries (1)

Q9XH32
RISB_SPIOL
Spinacia oleracea
6,7-dimethyl-8-ribityllumazine synthase, chloroplastic

PDB Structure

PDB 1C2Y
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure analysis of a pentameric fungal and an icosahedral plant lumazine synthase reveals the structural basis for differences in assembly.
Persson, K., Schneider, G., Jordan, D.B., Viitanen, P.V., Sandalova, T.
Protein Sci.
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