CATH Classification

Domain Context

CATH Clusters

Superfamily Glutaredoxin
Functional Family Glutathione S-transferase F2

Enzyme Information

2.5.1.18
Glutathione transferase.
based on mapping to UniProt P12653
RX + glutathione = HX + R-S-glutathione.
-!- A group of enzymes of broad specificity. -!- R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. -!- Also catalyzes the addition of aliphatic epoxides and arene oxides to glutathione, the reduction of polyol nitrate by glutathione to polyol and nitrile, certain isomerization reactions and disulfide interchange. -!- Formerly EC 1.8.6.1, EC 2.5.1.12, EC 2.5.1.13, EC 2.5.1.14 and EC 4.4.1.7.

UniProtKB Entries (1)

P12653
GSTF1_MAIZE
Zea mays
Glutathione S-transferase 1

PDB Structure

PDB 1BYE
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structures of herbicides in complex with their detoxifying enzyme glutathione S-transferase - explanations for the selectivity of the enzyme in plants.
Prade, L., Huber, R., Bieseler, B.
Structure