CATH Classification

Domain Context

CATH Clusters

Superfamily Aldehyde Dehydrogenase; Chain A, domain 2
Functional Family Mitochondrial aldehyde dehydrogenase 2

Enzyme Information

1.2.1.-
With NAD(+) or NADP(+) as acceptor.
based on mapping to UniProt P51977
1.2.1.36
Retinal dehydrogenase.
based on mapping to UniProt P51977
Retinal + NAD(+) + H(2)O = retinoate + NADH.
-!- Acts on both the 11-trans- and 13-cis-forms of retinal.

UniProtKB Entries (1)

P51977
AL1A1_SHEEP
Ovis aries
Retinal dehydrogenase 1

PDB Structure

PDB 1BXS
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Sheep liver cytosolic aldehyde dehydrogenase: the structure reveals the basis for the retinal specificity of class 1 aldehyde dehydrogenases.
Moore, S.A., Baker, H.M., Blythe, T.J., Kitson, K.E., Kitson, T.M., Baker, E.N.
Structure