CATH Classification

Domain Context

CATH Clusters

Superfamily Leucine Dehydrogenase, chain A, domain 1
Functional Family

Enzyme Information

1.4.1.20
Phenylalanine dehydrogenase.
based on mapping to UniProt Q59771
L-phenylalanine + H(2)O + NAD(+) = phenylpyruvate + NH(3) + NADH.
-!- The enzymes from Bacillus badius and Sporosarcina ureae are highly specific for L-phenylalanine; that from Bacillus sphaericus also acts on L-tyrosine.

UniProtKB Entries (1)

Q59771
DHPH_RHOSO
Rhodococcus sp.
Phenylalanine dehydrogenase

PDB Structure

PDB 1BW9
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Phenylalanine dehydrogenase from Rhodococcus sp. M4: high-resolution X-ray analyses of inhibitory ternary complexes reveal key features in the oxidative deamination mechanism.
Vanhooke, J.L., Thoden, J.B., Brunhuber, N.M., Blanchard, J.S., Holden, H.M.
Biochemistry