CATH Classification

Domain Context

CATH Clusters

Superfamily Golgi alpha-mannosidase II
Functional Family Pancreatic alpha-amylase

Enzyme Information

3.2.1.1
Alpha-amylase.
based on mapping to UniProt P00690
Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1->4)-alpha-linked D-glucose units.
-!- Acts on starch, glycogen and related polysaccharides and oligosaccharides in a random manner; reducing groups are liberated in the alpha-configuration. -!- The term 'alpha' relates to the initial anomeric configuration of the free sugar group released and not to the configuration of the linkage hydrolyzed.

UniProtKB Entries (2)

P00690
AMYP_PIG
Sus scrofa
Pancreatic alpha-amylase
P01092
IAA_STRTE
Streptomyces tendae
Alpha-amylase inhibitor HOE-467A

PDB Structure

PDB 1BVN
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The crystal structure of porcine pancreatic alpha-amylase in complex with the microbial inhibitor Tendamistat.
Wiegand, G., Epp, O., Huber, R.
J.Mol.Biol.