CATH Classification

Domain Context

CATH Clusters

Superfamily DD-peptidase/beta-lactamase superfamily
Functional Family Extended spectrum beta-lactamase GES-11

Enzyme Information

3.5.2.6
Beta-lactamase.
based on mapping to UniProt P62593
A beta-lactam + H(2)O = a substituted beta-amino acid.
-!- Zinc is only requires in class-B enzymes. -!- A group of enzymes of varying specificity hydrolyzing beta-lactams; some act more rapidly on penicillins, some more rapidly on cephalosporins. -!- Formerly EC 3.5.2.8.

UniProtKB Entries (1)

P62593
BLAT_ECOLX
Escherichia coli
Beta-lactamase TEM

PDB Structure

PDB 1BTL
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of Escherichia coli TEM1 beta-lactamase at 1.8 A resolution.
Jelsch, C., Mourey, L., Masson, J.M., Samama, J.P.
Proteins