CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module
Functional Family Ferredoxin--NADP reductase, chloroplastic

Enzyme Information

1.18.1.2
Ferredoxin--NADP(+) reductase.
based on mapping to UniProt P21890
2 reduced ferredoxin + NADP(+) + H(+) = 2 oxidized ferredoxin + NADPH.
-!- In chloroplasts and cyanobacteria the enzyme acts on plant-type [2Fe- 2S] ferredoxins, but in other bacteria it can also reduce bacterial 2[4Fe-4S] ferredoxins and flavodoxin. -!- Formerly EC 1.6.7.1 and EC 1.6.99.4.

UniProtKB Entries (1)

P21890
FENR_NOSSO
Nostoc sp. PCC 7119
Ferredoxin--NADP reductase

PDB Structure

PDB 1BQE
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Probing the determinants of coenzyme specificity in ferredoxin-NADP+ reductase by site-directed mutagenesis.
Medina, M., Luquita, A., Tejero, J., Hermoso, J., Mayoral, T., Sanz-Aparicio, J., Grever, K., Gomez-Moreno, C.
J.Biol.Chem.