CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.10 | Roll |
|
3.10.170 | Elastase; domain 1 |
|
3.10.170.10 |
Domain Context
CATH Clusters
| Superfamily | 3.10.170.10 |
| Functional Family |
Enzyme Information
| 3.4.24.29 |
Aureolysin.
based on mapping to UniProt P81177
Cleavage of insulin B chain with specificity similar to that of thermolysin, preferring hydrophobic P1' residues. Activates the glutamyl endopeptidase (EC 3.4.21.19) of Staphylococcus aureus.
-!- Earlier confused with staphylokinase. -!- Belongs to peptidase family M4. -!- Formerly EC 3.4.24.4 and EC 3.4.99.22.
|
UniProtKB Entries (1)
| P81177 |
AURE_STAAU
Staphylococcus aureus
Zinc metalloproteinase aureolysin
|
PDB Structure
| PDB | 1BQB |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Amino-acid sequence and three-dimensional structure of the Staphylococcus aureus metalloproteinase at 1.72 A resolution.
Structure
|
