CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.150 | Vaccinia Virus protein VP39 |
Domain Context
CATH Clusters
Superfamily | Vaccinia Virus protein VP39 |
Functional Family |
Enzyme Information
2.1.1.113 |
Site-specific DNA-methyltransferase (cytosine-N(4)-specific).
based on mapping to UniProt P11409
S-adenosyl-L-methionine + DNA cytosine = S-adenosyl-L-homocysteine + DNA N(4)-methylcytosine.
-!- This is a large group of enzymes, the majority of which, with enzymes of similar site specificity listed as EC 3.1.21.3, EC 3.1.21.4 and EC 3.1.21.5, form so-called restriction-modification systems. -!- See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/
|
UniProtKB Entries (1)
P11409 |
MTP2_PROHU
Proteus hauseri
Modification methylase PvuII
|
PDB Structure
PDB | 1BOO |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
Structure of pvu II DNA-(cytosine N4) methyltransferase, an example of domain permutation and protein fold assignment.
Nucleic Acids Res.
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