CATH Classification

Domain Context

CATH Clusters

Superfamily 1.10.10.390
Functional Family Histone acetyltransferase type B catalytic subunit

Enzyme Information

2.3.1.48
Histone acetyltransferase.
based on mapping to UniProt Q12341
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.
-!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.

UniProtKB Entries (1)

Q12341
HAT1_YEAST
Saccharomyces cerevisiae S288C
Histone acetyltransferase type B catalytic subunit

PDB Structure

PDB 1BOB
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of the histone acetyltransferase Hat1: a paradigm for the GCN5-related N-acetyltransferase superfamily.
Dutnall, R.N., Tafrov, S.T., Sternglanz, R., Ramakrishnan, V.
Cell(Cambridge,Mass.)