CATH Classification

Domain Context

CATH Clusters

Superfamily Ubiquinol cytochrome reductase, transmembrane domain
Functional Family Cytochrome b-c1 complex subunit Rieske, mitochondrial

Enzyme Information

1.10.2.2
Quinol--cytochrome-c reductase.
based on mapping to UniProt P13272
Quinol + 2 ferricytochrome c = quinone + 2 ferrocytochrome c + 2 H(+).
-!- The enzyme, often referred to as the cytochrome bc1 complex or complex III, is the third complex in the electron transport chain. -!- It is present in the mitochondria of all aerobic eukaryotes and in the inner membranes of most bacteria. -!- The mammalian enzyme contains cytochromes b-562, b-566 and C(1), and a 2-iron ferredoxin. -!- Depending on the organism and physiological conditions, the enzyme extrudes either two or four protons from the cytoplasmic to the non- cytoplasmic compartment (cf. EC 1.6.99.3).

UniProtKB Entries (1)

P07552
QCR10_BOVIN
Bos taurus
Cytochrome b-c1 complex subunit 10

PDB Structure

PDB 1BE3
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Complete structure of the 11-subunit bovine mitochondrial cytochrome bc1 complex.
Iwata, S., Lee, J.W., Okada, K., Lee, J.K., Iwata, M., Rasmussen, B., Link, T.A., Ramaswamy, S., Jap, B.K.
Science