CATH Classification

Domain Context

CATH Clusters

Superfamily Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
Functional Family Malate dehydrogenase

Enzyme Information

1.1.1.37
Malate dehydrogenase.
based on mapping to UniProt P10584
(S)-malate + NAD(+) = oxaloacetate + NADH.
-!- Also oxidizes some other 2-hydroxydicarboxylic acids.

UniProtKB Entries (1)

P10584
MDH_THETH
Thermus thermophilus
Malate dehydrogenase

PDB Structure

PDB 1BDM
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Determinants of protein thermostability observed in the 1.9-A crystal structure of malate dehydrogenase from the thermophilic bacterium Thermus flavus.
Kelly, C.A., Nishiyama, M., Ohnishi, Y., Beppu, T., Birktoft, J.J.
Biochemistry