CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.1120.10
Functional Family

Enzyme Information

3.1.6.8
Cerebroside-sulfatase.
based on mapping to UniProt P15289
A cerebroside 3-sulfate + H(2)O = a cerebroside + sulfate.
-!- Hydrolyzes galactose-3-sulfate residues in a number of lipids. -!- Also hydrolyzes ascorbate 2-sulfate and many phenol sulfates.

UniProtKB Entries (1)

P15289
ARSA_HUMAN
Homo sapiens
Arylsulfatase A

PDB Structure

PDB 1AUK
External Links
Method X-RAY DIFFRACTION
Organism Mesocricetus
Primary Citation
Crystal structure of human arylsulfatase A: the aldehyde function and the metal ion at the active site suggest a novel mechanism for sulfate ester hydrolysis.
Lukatela, G., Krauss, N., Theis, K., Selmer, T., Gieselmann, V., von Figura, K., Saenger, W.
Biochemistry