CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.1380 | Pyruvate Kinase; Chain: A, domain 1 |
|
3.40.1380.20 | Pyruvate kinase, C-terminal domain |
Domain Context
CATH Clusters
| Superfamily | Pyruvate kinase, C-terminal domain |
| Functional Family | Pyruvate kinase |
Enzyme Information
| 2.7.1.40 |
Pyruvate kinase.
based on mapping to UniProt P11974
ATP + pyruvate = ADP + phosphoenolpyruvate.
-!- UTP, GTP, CTP, ITP and dATP can also act as donors. -!- Also phosphorylates hydroxylamine and fluoride in the presence of CO(2).
|
UniProtKB Entries (1)
| P11974 |
KPYM_RABIT
Oryctolagus cuniculus
Pyruvate kinase PKM
|
PDB Structure
| PDB | 1AQF |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Ligand-induced domain movement in pyruvate kinase: structure of the enzyme from rabbit muscle with Mg2+, K+, and L-phospholactate at 2.7 A resolution.
Arch.Biochem.Biophys.
|