CATH Classification

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family Anionic trypsin-2

Enzyme Information

3.4.21.4
Trypsin.
based on mapping to UniProt P00763
Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.
-!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.4.

UniProtKB Entries (1)

P00763
TRY2_RAT
Rattus norvegicus
Anionic trypsin-2

PDB Structure

PDB 1ANB
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Perturbing the polar environment of Asp102 in trypsin: consequences of replacing conserved Ser214.
McGrath, M.E., Vasquez, J.R., Craik, C.S., Yang, A.S., Honig, B., Fletterick, R.J.
Biochemistry