CATH Classification

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family Anionic trypsin

Enzyme Information

3.4.21.4
Trypsin.
based on mapping to UniProt P00761
Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.
-!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.4.

UniProtKB Entries (2)

P00761
TRYP_PIG
Sus scrofa
Trypsin
P80424
LDTI_HIRME
Hirudo medicinalis
Leech-derived tryptase inhibitor C

PDB Structure

PDB 1AN1
External Links
Method X-RAY DIFFRACTION
Organism Saccharomyces
Primary Citation
Structure of the complex of leech-derived tryptase inhibitor (LDTI) with trypsin and modeling of the LDTI-tryptase system.
Di Marco, S., Priestle, J.P.
Structure