CATH Classification

Domain Context

CATH Clusters

Superfamily alpha/beta hydrolase
Functional Family Acetylcholinesterase

Enzyme Information

3.1.1.7
Acetylcholinesterase.
based on mapping to UniProt P04058
Acetylcholine + H(2)O = choline + acetate.
-!- Acts on a variety of acetic esters. -!- Also catalyzes transacetylations.

UniProtKB Entries (1)

P04058
ACES_TETCF
Tetronarce californica
Acetylcholinesterase

PDB Structure

PDB 1AMN
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The X-ray structure of a transition state analog complex reveals the molecular origins of the catalytic power and substrate specificity of acetylcholinesterase.
Harel, M., Quinn, D.M., Nair, H.K., Silman, I., Sussman, J.L.
J.Am.Chem.Soc.