CATH Classification

Domain Context

CATH Clusters

Superfamily Type I PLP-dependent aspartate aminotransferase-like (Major domain)
Functional Family Aspartate aminotransferase

Enzyme Information

2.6.1.3
Cysteine transaminase.
based on mapping to UniProt P00503
L-cysteine + 2-oxoglutarate = mercaptopyruvate + L-glutamate.
2.6.1.1
Aspartate transaminase.
based on mapping to UniProt P00503
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.
-!- Also acts on L-tyrosine, L-phenylalanine and L-tryptophan. -!- This activity can be formed from EC 2.6.1.57 by controlled proteolysis.

UniProtKB Entries (1)

P00503
AATC_PIG
Sus scrofa
Aspartate aminotransferase, cytoplasmic

PDB Structure

PDB 1AJR
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Refinement and comparisons of the crystal structures of pig cytosolic aspartate aminotransferase and its complex with 2-methylaspartate.
Rhee, S., Silva, M.M., Hyde, C.C., Rogers, P.H., Metzler, C.M., Metzler, D.E., Arnone, A.
J.Biol.Chem.