CATH Classification

Domain Context

CATH Clusters

Superfamily Alkaline Phosphatase, subunit A
Functional Family Alkaline phosphatase

Enzyme Information

3.1.3.1
Alkaline phosphatase.
based on mapping to UniProt P00634
A phosphate monoester + H(2)O = an alcohol + phosphate.
-!- Active at a high pH optimum. -!- Wide specificity. -!- Also catalyzes transphosphorylations. -!- Some enzymes hydrolyze diphosphate (cf. EC 3.6.1.1).

UniProtKB Entries (1)

P00634
PPB_ECOLI
Escherichia coli K-12
Alkaline phosphatase

PDB Structure

PDB 1AJC
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystallographic analysis of reversible metal binding observed in a mutant (Asp153-->Gly) of Escherichia coli alkaline phosphatase.
Dealwis, C.G., Brennan, C., Christianson, K., Mandecki, W., Abad-Zapatero, C.
Biochemistry