CATH Classification

Domain Context

CATH Clusters

Superfamily Aspartate Aminotransferase, domain 1
Functional Family

Enzyme Information

2.6.1.1
Aspartate transaminase.
based on mapping to UniProt P00509
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.
-!- Also acts on L-tyrosine, L-phenylalanine and L-tryptophan. -!- This activity can be formed from EC 2.6.1.57 by controlled proteolysis.

UniProtKB Entries (1)

P00509
AAT_ECOLI
Escherichia coli K-12
Aspartate aminotransferase

PDB Structure

PDB 1AIA
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural basis for the catalytic activity of aspartate aminotransferase K258H lacking the pyridoxal 5'-phosphate-binding lysine residue.
Malashkevich, V.N., Jager, J., Ziak, M., Sauder, U., Gehring, H., Christen, P., Jansonius, J.N.
Biochemistry