CATH Classification

Domain Context

CATH Clusters

Superfamily Pyruvate kinase, C-terminal domain
Functional Family Pyruvate kinase

Enzyme Information

2.7.1.40
Pyruvate kinase.
based on mapping to UniProt P00549
ATP + pyruvate = ADP + phosphoenolpyruvate.
-!- UTP, GTP, CTP, ITP and dATP can also act as donors. -!- Also phosphorylates hydroxylamine and fluoride in the presence of CO(2).

UniProtKB Entries (1)

P00549
KPYK1_YEAST
Saccharomyces cerevisiae S288C
Pyruvate kinase 1

PDB Structure

PDB 1A3W
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The allosteric regulation of pyruvate kinase by fructose-1,6-bisphosphate.
Jurica, M.S., Mesecar, A., Heath, P.J., Shi, W., Nowak, T., Stoddard, B.L.
Structure