CATH Classification

Domain Context

CATH Clusters

Superfamily 2.40.50.90
Functional Family Thermonuclease

Enzyme Information

3.1.31.1
Micrococcal nuclease.
based on mapping to UniProt P00644
Endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotide end-products.
-!- Hydrolyzes double- or single-stranded substrate. -!- Similar enzymes: Chlamydomonas nuclease, spleen phosphodiesterase, spleen endonuclease. -!- Formerly EC 3.1.4.7.

UniProtKB Entries (1)

P00644
NUC_STAAU
Staphylococcus aureus
Thermonuclease

PDB Structure

PDB 1A3V
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Comparison of straight chain and cyclic unnatural amino acids embedded in the core of staphylococcal nuclease.
Wynn, R., Harkins, P.C., Richards, F.M., Fox, R.O.
Protein Sci.