CATH Classification

CATH Clusters

Superfamily Copper amine oxidase, Domain 3
Functional Family Copper amine oxidase 1

Enzyme Information
Primary-amine oxidase.
based on mapping to UniProt P12807
RCH(2)NH(2) + H(2)O + O(2) = RCHO + NH(3) + H(2)O(2).
-!- A group of enzymes that oxidize primary monoamines but have little or no activity toward diamines, such as histamine, or toward secondary and tertiary amines. -!- They are copper quinoproteins (2,4,5-trihydroxyphenylalanine quinone) and, unlike EC, are sensitive to inhibition by carbonyl-group reagents, such as semicarbazide. -!- In some mammalian tissues the enzyme also functions as a vascular- adhesion protein (VAP-1). -!- Formerly EC

UniProtKB Entries (1)

Ogataea angusta
Peroxisomal primary amine oxidase

PDB Structure

External Links
Primary Citation