CATH Domain 1a2vA01
|3.10.450||Nuclear Transport Factor 2; Chain: A,|
based on mapping to UniProt P12807
RCH(2)NH(2) + H(2)O + O(2) = RCHO + NH(3) + H(2)O(2).
-!- A group of enzymes that oxidize primary monoamines but have little or no activity toward diamines, such as histamine, or toward secondary and tertiary amines. -!- They are copper quinoproteins (2,4,5-trihydroxyphenylalanine quinone) and, unlike EC 220.127.116.11, are sensitive to inhibition by carbonyl-group reagents, such as semicarbazide. -!- In some mammalian tissues the enzyme also functions as a vascular- adhesion protein (VAP-1). -!- Formerly EC 18.104.22.168.
UniProtKB Entries (1)
Peroxisomal primary amine oxidase
Crystallographic study of yeast copper amine oxidase.