CATH Classification

Domain Context

CATH Clusters

Superfamily Phospholipase A2 domain
Functional Family Basic phospholipase A2 homolog

Enzyme Information

3.1.1.4
Phospholipase A(2).
based on mapping to UniProt P14421
Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate.
-!- Also acts on phosphatidylethanolamine, choline plasmalogen and phosphatides, removing the fatty acid attached to the 2-position.

UniProtKB Entries (1)

P14421
PA2N_GLOHA
Gloydius halys
Neutral phospholipase A2 agkistrodotoxin

PDB Structure

PDB 1A2A
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of agkistrodotoxin, a phospholipase A2-type presynaptic neurotoxin from agkistrodon halys pallas.
Tang, L., Zhou, Y.C., Lin, Z.J.
J.Mol.Biol.