CATH Classification

Domain Context

CATH Clusters

Superfamily 1.25.40.10
Functional Family Serine/threonine-protein phosphatase PP-V, putative

Enzyme Information

3.1.3.16
Protein-serine/threonine phosphatase.
based on mapping to UniProt P53041
[a protein]-serine/threonine phosphate + H(2)O = [a protein]- serine/threonine + phosphate.
-!- A group of enzymes removing the serine- or threonine-bound phosphate group from a wide range of phosphoproteins, including a number of enzymes which have been phosphorylated under the action of a kinase (cf. EC 3.1.3.48). -!- The spleen enzyme also acts on phenolic phosphates and phosphamides (cf. EC 3.9.1.1).

UniProtKB Entries (1)

P53041
PPP5_HUMAN
Homo sapiens
Serine/threonine-protein phosphatase 5

PDB Structure

PDB 1A17
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The structure of the tetratricopeptide repeats of protein phosphatase 5: implications for TPR-mediated protein-protein interactions.
Das, A.K., Cohen, P.W., Barford, D.
EMBO J.