View in Gene3D

CATH Superfamily 3.40.1000.70

PknH-like extracellular domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
PknH-like extracellular domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: PknH-like extracellular domain

According to the literature, members of the structural domains which comprise this superfamily correspond to the structure of the extracellular, C-terminal, sensor domain of a group of protein kinases of which PknH is the best characterised. These type of protein kinases are which are mainly found in mycobacteria.

Structural studies have shown a ligand binding cleft and therefore suggest that sensor-domain homologues are involved in the binding of related ligands all involved in the regulation of kinase localization or oligomerization PMID:22727744.

GO Diversity

Unique GO annotations
17 Unique GO terms

EC Diversity

Unique EC annotations
1 Unique EC terms

Species Diversity

Unique species annotations
394 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 1
Domain clusters (>95% seq id): 1
Domain clusters (>35% seq id): 1
Unique PDBs: 1
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 5
Function
Unique EC: 1
Unique GO: 17
Taxonomy
Unique Species: 394