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CATH Superfamily 2.30.29.70

Proteasomal ubiquitin receptor Rpn13/ADRM1

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Proteasomal ubiquitin receptor Rpn13/ADRM1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Proteasomal ubiquitin receptor Rpn13/ADRM1

Proteasomal receptors that recognize ubiquitin chains attached to substrates are key mediators of selective protein degradation in eukaryotes. Structural domains comprising this superfamily share the structure of the ubiquitin receptor, Rpn13/ARM1, a known component of the proteasome. Rpn13 binds ubiquitin via a conserved N-terminal region termed the Pru domain (Pleckstrin-like receptor for ubiquitin) PMID:18497817, PMID:18497827.

This entry includes Rpn13 from budding yeasts and its homologue ADRM1 from animals.

GO Diversity

Unique GO annotations
36 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
1403 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 15
Domain clusters (>95% seq id): 2
Domain clusters (>35% seq id): 2
Unique PDBs: 12
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 19
Function
Unique EC:
Unique GO: 36
Taxonomy
Unique Species: 1403