PDB 6s41

PDB Information

PDB6S41
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Identification of CNS-Penetrant Aryl Sulfonamides as Isoform-Selective NaV1.6 Inhibitors with Efficacy in Mouse Models of Epilepsy.
Focken, T., Burford, K., Grimwood, M.E., Zenova, A., Andrez, J.C., Gong, W., Wilson, M., Taron, M., Decker, S., Lofstrand, V., Chowdhury, S., Shuart, N., Lin, S., Goodchild, S.J., Young, C., Soriano, M., Tari, P.K., Waldbrook, M., Nelkenbrecher, K., Kwan, R., Lindgren, A., de Boer, G., Lee, S., Sojo, L., DeVita, R.J., Cohen, C.J., Wesolowski, S.S., Johnson Jr., J.P., Dehnhardt, C.M., Empfield, J.R.
J.Med.Chem.
HeaderNuclear Protein
Released2019-06-26
Resolution2.700
CATH Insert Date06 Oct, 2019

PDB Images (1)

PDB Prints

PDB Chains (0)

Chain ID Date inserted into CATH CATH Status

CATH Domains (0)

Domain ID Date inserted into CATH Superfamily CATH Status

UniProtKB Entries (0)

Accession Gene ID Taxon Description