PDB 6r8x

PDB Information

PDB6R8X
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
MAA868, a novel FXI antibody with a unique binding mode, shows durable effects on markers of anticoagulation in humans.
Koch, A.W., Schiering, N., Melkko, S., Ewert, S., Salter, J., Zhang, Y., McCormack, P., Yu, J., Huang, X., Chiu, Y.H., Chen, Z., Schleeger, S., Horny, G., DiPetrillo, K., Muller, L., Hein, A., Villard, F., Scharenberg, M., Ramage, P., Hassiepen, U., Cote, S., DeGagne, J., Krantz, C., Eder, J., Stoll, B., Kulmatycki, K., Feldman, D.L., Hoffmann, P., Basson, C.T., Frost, R.J.A., Khder, Y.
Blood
HeaderBlood Clotting
Released2019-04-02
Resolution2.040
CATH Insert Date14 Apr, 2019

PDB Images (8)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 14 Apr, 2019 Chopped
B 14 Apr, 2019 Chopped
C 14 Apr, 2019 Holding pen

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
6r8xA01 15 Apr, 2019 Holding pen
6r8xA02 15 Apr, 2019 2.40.10.10 Assigned
6r8xB01 15 Apr, 2019 2.60.40.10 Assigned
6r8xB02 15 Apr, 2019 2.60.40.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P03951 FA11_HUMAN Homo sapiens Coagulation factor XI